First Amendment To Construction Services Agreement

Exhibit 10.39

First Amendment

to the Construction Agreement between The Henderson Corporation and Dendreon Corporation

THIS FIRST AMENDMENT to the Construction Agreement (the " First Amendment" ) dated as of April 4, 2006, is entered into by and between Dendreon Corporation, having an office at 3005 First Avenue, Seattle, WA, 98121 (" Owner" ) and The Henderson Corporation, having an office at 575 State Hwy. 28, Raritan, NJ, 08869 (" Contractor" ).

WHEREAS, Contractor and Owner entered into a Construction Agreement dated November 4, 2005 (the " Agreement" ); and

WHEREAS, Contractor and Owner entered into Change Order No. 1 dated December 13, 2005 (" Change Order No. 1" ); and

WHEREAS, Contractor and Owner desire to amend the Agreement and Change Order No. 1 to reflect certain changed conditions and the new understanding between the parties as set forth below; NOW THEREFORE, in consideration of the mutual covenants and agreements contained herein, the parties hereto agree as follows: 1. Scope of the Work .

Section 2.01 of the Agreement is hereby replaced in its entirety with the following provision:

Contractor shall perform all Construction services described in this Agreement in connection with the construction of the Work. The general scope of the Work is set forth in the Redesign Meeting Notes dated January 5-6, 2006, the layout as depicted in Perkins + Will drawing identified as 06.01.16 and the Further Reduced Scope Estimate, all of which are attached hereto as Exhibit A, and further as follows:

The scope of work is revised to reduce the size of the New Jersey manufacturing facility from a 48 workstation facility to a 12 workstation facility with appropriate laboratory and support areas.

Owner shall be responsible for obtaining all consents, licenses and easements required from adjoining property owners. 2. Contract Sum .

a. Section 3.01 of the Agreement is hereby deleted in its entirety and replaced with the following: As consideration for the full and complete performance of the Work and all of Contractor' s obligations hereunder, Owner shall pay to Contractor a sum of money (" Contract Sum" ) equal to the total of:

(i) a fee (" Contractor' s Fee" ) Contractor' s Fee includes all overhea ...