Research And Development Contract

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Section B - Supplies or Services and Prices



B.1. TYPE OF CONTRACT

This is a cost plus fixed fee completion form type contract pursuant to FAR 16.306(d)(1).



B.2. The cost principles and procedures in subpart 31.103 of the Federal Acquisition Regulation (FAR) are incorporated by reference for determining reimbursable costs per FAR 31.2 as appropriate.






ITEM NO SUPPLIES/SERVICES QUANTITY UNIT UNIT PRICE AMOUNT
0001
BAA Effort



CPFF



BAA Effort as set forth in the SOW and the Contractor's proposal. The contractor, as an independent contractor and not as an agent of the Government, shall furnish the necessary resources (except those specifically designated as Government-furnished) to perform the work as detailed in the Broad Agency Announcement proposal entitled: "Development of a CMOS Microarray Platform for Bio and Chemical Threat Agent Detection", specifically pages 5-10, dated 1 Sep 2006, and submitted by CombiMatrix.



FOB: Destination




ESTIMATED COST

$2,083,085.00
FIXED FEE $129,432.00


TOTAL EST COST + FEE $2,212,517.00
ACRN AA

CIN: 000000000000000000000000000000

$2,212,517.00









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Section C - Descriptions and Specifications



OTHER INFORMATION

SECTION C: DESCRIPTION/SPECIFICATIONS/WORK STATEMENTS



TITLE: Development of a CMOS Microarray Platform for Bio and Chemical Threat Agent Detection



C.1.0 Scope . This work effort encompasses development of a biological and chemical agent point detector based on electrochemical detection of agents on CMOS microarrays. The effort will entail development and production of two new microarray designs, development and fabrication of a new prototype instrument that supports automated sample processing, genomic and serological assays and electrochemical detection (ECD), develop and evaluate different bioinformatics approaches and genomic assays for detecting specific biothreat agents (BTAs), systems integration of hardware, software, and assays for a fully functional and automated bio/chem detection system, and validating Quality Assurance and /Quality Control (QA/QC) processes to reduce the costs and improve performance of microarrays.



C.1.1 Background . In the Modernization Plan 2004, the JRO-CBRN recognized serious shortcomings in current platforms for the point detection of BTAs and chemical threat agents (CTAs) . Size, weight, ability to detect diverse agents, reduced false alarm rates, accuracy, and sensitivity were identified as common problems with current technologies. In response, the Defense Threat Reduction Agency (DTRA) is emphasizing the optimization of sensor technologies with a focused effort on multi-agent sensors for chemical and biological (CB) agents to include non-traditional agents, emerging threat agents and toxic industrial chemicals/materials. In addition, DTRA has a new nanotechnology initiative to identify novel nanoscale approaches that can be applied to CB point detection array analysis.



C.1.2 Objective . . To continue development of an automated biothreat agent (BTA) detection system based upon the CombiMatrix complementary metal oxide semiconductor (CMOS) microarray and electrochemical detection (ECD); to continue the integration of serological and genomic assays for orthogonal testing; and to explore new methods of detection that expand target identification, reduce reagent burden, and improve assay time.



C.2.0 Applicable Documents . None.



C.3.0 Requirements .



C.3.1 General. The contractor, as an independent contractor and not as an agent of the Government, shall furnish the necessary resources (except those specifically designated as Government-furnished) to perform the work as detailed in the Broad Agency Announcement proposal entitled: "Development of a CMOS Microarray Platform for Bio and Chemical Threat Agent Detection", specifically pages 5-10, dated 1 September 2006, and submitted by CombiMatrix, Inc.



C.3.2 Safety .



C.3.2.1 The contractor shall notify all local emergency support agencies (such as law enforcement, fire department, health departments and government) of Biological Defense Program activities and ensure the appropriate emergency support is available to provide effective emergency response. The contractor shall formalize all required support agreements with local agencies.



C.3.2.1.2 The contractor shall notify the government Contracting Officer's Representative of any biological defense mishaps related to this contract within 24 hours. No government reply is required.







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C.3.2.1.3 The contractor shall make facilities used to support this contract accessible to government representatives for periodic safety compliance inspections. The contractor shall correct all major deficiencies noted during safety compliance inspections prior to beginning or continuing operations in accordance with the government's instructions.



C.3.2.1.4 The contractor shall submit a safety assessment report in accordance with Exhibit Line Item Number (ELIN) A003. for new developed or modified equipment prior to transport to Department of the Army for evaluation.



C.3.3 Security .



C.3.3.1 This contract is unclassified and does not contain security requirements or a Contract Security Classification Specification, DD Form 254. However, the Government may require Operational Security (OPSEC) measures (when applicable) to protect sensitive unclassified contract information. If access to unclassified sensitive information (For Official Use Only - FOUO) is authorized, contractor may access only the information related to the subject matter of this contract.



C.3.3.2 The contractor shall not use foreign nationals on this contract unless approved by the Contracting Officer. When requesting approval, the contractor shall furnish full name, date of birth, place of birth, citizenship, registration number, type of visa, port of entry, and type of position in which employee will be utilized. Previously approved foreign nationals must be re-approved if the nature of their work under this contract differs from that performed under the prior year ?s contract. The Contractor shall submit a copy of the work visa or green card with an abbreviated Curriculum Vitae and a justification to the Contract Specialist for review by the Security Office and subsequent approval by the Contracting Officer.



C.3.3.3 Should the government determine that the technology has developed to a point where the information warrants protection, a DD Form 254 and an approved classification guide will be issued.



C.3.4 Administration .



C.3.4.1 Reporting.



C.3.4.1.1 The contractor shall provide progress reports in accordance with (IAW) Exhibit Line Item Number (ELIN) A001.



C.3.4.1.2 The contractor shall provide a final comprehensive report IAW ELIN A002. The final report shall include detailed descriptions of the work accomplished.



C.3.4.1.2.1 The contractor shall provide the synthesis procedures and QA/QC procedures as appendices to the draft final report (IAW ELIN A002).



C.3.4.1.3 For any publication of a technical paper or presentation resulting from this contract, the Contractor shall make attribution to and include as a co-author those Government personnel who made research contributions to the contract subject matter being published in the same manner and to the same extent as the principle author would do so for it's own peers, assistants, or students.



C.3.4.2 Contractor Manpower Reporting. . The contractor shall perform manpower reporting as follows:







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C.3.4.2.1 The contractor shall report all contractor manpower (including subcontractor manpower) required for performance of this contract using the format provided at the following web address: https://cmra.army.mil . The contractor shall report directly to the website. The contractor shall include the following:



Contract Number

Delivery Order Number (If applicable)

Task Order Number (If applicable)

Requiring Activity Unit Identification Code (W1D101)

Command (Edgewood Chemical Biological Center)

Contractor Contact Information

Federal Service Code

Direct Labor Hours

Direct Labor Dollars

Location Information



Contract Number - Always 13 characters long, usually beginning with a unit code, like W911SR. Enter the full number without dashes.



Delivery Order Number - Usually 13 characters long. Enter with no dashes. Many contracts have multiple Delivery Orders. Each must be entered.



Task Order Number - Usually 13 characters long. Enter with no dashes. Services contracts are often created with Task Orders as opposed to Delivery Orders.



Requiring Activity UIC - The Unit Identification Code of the unit for which the service is being performed - meaning the unit the requested the service, which is not necessarily, but may be, the unit that contracted for the service.



Command - From the drop down arrow, select the Army Command for the unit reflected in the Requiring Activity UIC .



Total Obligated Dollars - The total dollar amount obligated during the fiscal year, at the Delivery Order or Task Order level.



Total Disbursements - The total dollar amount disbursed during the fiscal year, at the Delivery Order and/or Task Order level.



C.3.4.2.2 The contractor shall also provide the estimated total cost (if any) (CLIN 0002) incurred to comply with this reporting requirement. The reporting period shall be the period of performance not to exceed 12 months ending 30 September of each government fiscal year and must be reported by 31 October of each calendar year.The contractor shall perform manpower reporting as follows:



C.3.4.2.3 The contractor shall report all contractor manpower (including subcontractor manpower) required for performance of this contract using the format provided at the following web address: https://contractormanpower.army.pentagon.mil . The contractor shall include the following:



(a) Contracting Office, Contracting Officer, Contracting Officer's Technical Representative
(b) Contract number, including task and delivery order number
(c) Beginning and ending dates covered by reporting period
(d) Contractor name, address, phone number, e-mail address, identity of contractor employee entering data
(e) Estimated direct labor hours (including subcontractors)
(f) Estimated direct labor hours paid this reporting period (including subcontractors)
(g) Total payments (including subcontractors)
(h) Predominant Federal Service Code (FSC) reflecting services provided by contractor (and separate predominant FSC fore each sub-contractor if different)
(i) Estimated data collection cost
(j) Organizational title associated with the Unique Identification Code (UIC W91B94) for the Army Requiring Activity.
(k) Locations where contractor and subcontractors perform the work (specified by zip code in the United States and nearest city, country, when in an overseas location, using standardized nomenclature provided on the website.
(l) Presence of deployment or contingency contract language
(m) Number of contractor and subcontractor employees deployed in theater this reporting period (by country).









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C.3.4.2.4 The contractor shall also provide the estimated total cost (if any) incurred to comply with this reporting requirement. The reporting period shall be the period of performance not to exceed 12 months ending 30 September of each government fiscal year and must be reported by 3 October of each calendar year.



C.3.4.2.5 The contractor may use a direct XML data transfer to the database server or fill in the fields on the website. The XML direct transfer is a format for transferring files from a contractor's system to the secure web site without the need for separate data entries fore each required data element at the web site. The specific formats for the XML direct transfer may be downloaded from the web site.



Section D - Packaging and Marking



SECTION D- PACKAGING & MARKING

D.1. Hardware. All items to be delivered by the Contractor under this contract shall be packed and packaged in accordance with good commercial practices and in such a manner that will afford protection against corrosion, deterioration and physical damage for safe delivery to destination.



D.2. Data. All data to be delivered by the Contractor under this contract shall be transmitted electronically.



Section E - Inspection and Acceptance



E.1 INSPECTION AND ACCEPTANCE

E.1.1. Hardware: Inspection and acceptance of all items delivered by the Contractor under this contract shall be at destination by the Contracting Officer's Representative (COR).



E.1.2. Data: Inspection and acceptance of data items will be performed by the first addressee identif ...