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Agreement#: AG-456089
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American Clinical Research Consultants Inc.

Effective Date: November 10, 1999
Parties:

Torreypines Therapeutics

Sectors: Biotechnology / Pharmaceuticals
EXHIBIT 10.23


Dr. Robert Burford

President

American Clinical Research Consultants Inc.

PO Box 7299

Wilton, CT 06897-7299


November 10, 1999


Dear Dr. Burford:


On behalf of the Board and management of Axonyx, I am delighted to memorialize the substance of your recent conversations with Dr. Hausman, concerning your employment by Axonyx:


1. You will be employed commencing on the date of your countersigning this letter as Vice-President, Product Development of Axonyx Inc.


2. Your salary compensation will be $100,000 per annum until either August 1, 2000, or September 1, 2000 (the appropriate date to be agreed to by the end of July, in accordance with your discussions with Dr. Hausman), after which it ...

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