Vice President of Human Resources Employment Agreement

EMPLOYMENT AGREEMENT


THIS EMPLOYMENT AGREEMENT (hereinafter the "Agreement"), made this 1st day of January, 1999, by and between Pharmaceutical Product Development, Inc., a North Carolina corporation with its principal office at 3151 17th Street Extension, Wilmington, North Carolina 28412 (hereinafter "PPD"), and David R. Williams (hereinafter "Employee").


RECITALS:


A. Employee desires employment upon the terms and conditions herein stated.


B. PPD desires to employ Employee upon the terms and conditions herein stated.


C. Employee and PPD desire to embody in writing the terms and conditions of such employment in this Agreement.


NOW, THEREFORE, in consideration of the mutual promises, covenants and considerations contained herein, and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereby agree as follows:


1. Employment. PPD hereby employs Employee and Employee hereby accepts such employment on a full time basis as Senior Vice President of Human Resources upon the terms and conditions hereinafter set forth.


2. Term. The term of this Agreement shall be for one year, beginning January 1, 1999, and ending December 31, 1999, unless sooner terminated as provided herein. Thereafter, this Agreement shall be automatically renewed for successive one-year terms upon the terms and conditions herein set forth and subject to salary adjustments as provided for in paragraph 9 below, unless either party gives notice as herein provided to the other of said party's intent not renew this Agreement not less than 60 days prior to the expiration of the one-year term then in effect.


3. Salary. For all services rendered by Employee under this Agreement, PPD Pharmaco shall pay to Employee an annual salary of $150,000 for the initial one-year term hereof.


4. Duties. Employee shall have overall responsibility for and, in consultation with executive management, decision making authority necessary to fulfill the duties of Senior Vice President of Human Resources. Employee shall undertake such travel as required to perform the duties prescribed herein. During the term of this


Agreement, Employee shall devote substantially all of his working time, attention and energies to the business of PPD.


5. Working Facilities. PPD shall furnish Employee with office space, equipment, technical, secretarial and clerical assistance and such other facilities, services, support and supplies as may be reasonably needed to perform the duties herein prescribed in an efficient and professional manner.


6. Non-Compete. During the term of this Agreement, Employee hereby agrees that he shall not (a) become an officer, employee, director, agent, representative, member, associate or consultant of or to a corporation, partnership or other business entity or person, (b) directly or indirectly acquire a proprietary interest in a corporation, partnership or other business entity or person, or (c) directly or indirectly own any stock in a corporation (other than a publicly traded corporation of which Employee owns less than five percent (5%) of the outstanding stock) which is engaged in the business of managing clinical research programs for pharmaceutical and medical products or in any other business which is developed by PPD during the term of this Agreement anywhere in the United States (whether or not such business is physically located within the United States). The parties agree that the business and operations of PPD are national in scope. For that reason, the parties agree that a geographical limitation on the foregoing covenant is not appropriate.


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